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Hippocampal CA3 Transcriptome Signature Correlates with Initial Precipitating Injury in Refractory Mesial Temporal Lobe Epilepsy

BACKGROUND: Prolonged febrile seizures constitute an initial precipitating injury (IPI) commonly associated with refractory mesial temporal lobe epilepsy (RMTLE). In order to investigate IPI influence on the transcriptional phenotype underlying RMTLE we comparatively analyzed the transcriptomic sign...

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Detalles Bibliográficos
Autores principales: Bando, Silvia Y., Alegro, Maryana C., Amaro, Edson, Silva, Alexandre V., Castro, Luiz H. M., Wen, Hung-Tzu, Lima, Leandro de A., Brentani, Helena, Moreira-Filho, Carlos Alberto
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3194819/
https://www.ncbi.nlm.nih.gov/pubmed/22022585
http://dx.doi.org/10.1371/journal.pone.0026268