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Hippocampal CA3 Transcriptome Signature Correlates with Initial Precipitating Injury in Refractory Mesial Temporal Lobe Epilepsy
BACKGROUND: Prolonged febrile seizures constitute an initial precipitating injury (IPI) commonly associated with refractory mesial temporal lobe epilepsy (RMTLE). In order to investigate IPI influence on the transcriptional phenotype underlying RMTLE we comparatively analyzed the transcriptomic sign...
Autores principales: | Bando, Silvia Y., Alegro, Maryana C., Amaro, Edson, Silva, Alexandre V., Castro, Luiz H. M., Wen, Hung-Tzu, Lima, Leandro de A., Brentani, Helena, Moreira-Filho, Carlos Alberto |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2011
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3194819/ https://www.ncbi.nlm.nih.gov/pubmed/22022585 http://dx.doi.org/10.1371/journal.pone.0026268 |
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