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Connexin43 Modulates Cell Polarity and Directional Cell Migration by Regulating Microtubule Dynamics

Knockout mice deficient in the gap junction gene connexin43 exhibit developmental anomalies associated with abnormal neural crest, primordial germ cell, and proepicardial cell migration. These migration defects are due to a loss of directional cell movement, and are associated with abnormal actin st...

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Detalles Bibliográficos
Autores principales: Francis, Richard, Xu, Xin, Park, Hyunsoo, Wei, Chin-Jen, Chang, Stephen, Chatterjee, Bishwanath, Lo, Cecilia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3194834/
https://www.ncbi.nlm.nih.gov/pubmed/22022608
http://dx.doi.org/10.1371/journal.pone.0026379