Cargando…

In Vivo Analysis of Conserved C. elegans Tomosyn Domains

Neurosecretion is critically dependent on the assembly of a macromolecular complex between the SNARE proteins syntaxin, SNAP-25 and synaptobrevin. Evidence indicates that the binding of tomosyn to syntaxin and SNAP-25 interferes with this assembly, thereby negatively regulating both synaptic transmi...

Descripción completa

Detalles Bibliográficos
Autores principales: Burdina, Anna O., Klosterman, Susan M., Shtessel, Ludmila, Ahmed, Shawn, Richmond, Janet E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3195084/
https://www.ncbi.nlm.nih.gov/pubmed/22022557
http://dx.doi.org/10.1371/journal.pone.0026185