Cargando…
Detailed kinetics and regulation of mammalian 2-oxoglutarate dehydrogenase
BACKGROUND: Mitochondrial 2-oxoglutarate (α-ketoglutarate) dehydrogenase complex (OGDHC), a key regulatory point of tricarboxylic acid (TCA) cycle, plays vital roles in multiple pathways of energy metabolism and biosynthesis. The catalytic mechanism and allosteric regulation of this large enzyme com...
Autores principales: | , , , |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2011
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3195097/ https://www.ncbi.nlm.nih.gov/pubmed/21943256 http://dx.doi.org/10.1186/1471-2091-12-53 |