Multiple search methods for similarity-based virtual screening: analysis of search overlap and precision

BACKGROUND: Data fusion methods are widely used in virtual screening, and make the implicit assumption that the more often a molecule is retrieved in multiple similarity searches, the more likely it is to be active. This paper tests the correctness of this assumption. RESULTS: Sets of 25 searches us...

Descripción completa

Detalles Bibliográficos
Autores principales: Holliday, John D, Kanoulas, Evangelos, Malim, Nurul, Willett, Peter
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2011
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3195112/
https://www.ncbi.nlm.nih.gov/pubmed/21824430
http://dx.doi.org/10.1186/1758-2946-3-29

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3195112/
https://www.ncbi.nlm.nih.gov/pubmed/21824430
http://dx.doi.org/10.1186/1758-2946-3-29

Ejemplares similares