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Bacterial Pili exploit integrin machinery to promote immune activation and efficient blood-brain barrier penetration

Group B Streptococcus (GBS) is the leading cause of meningitis in newborn infants. Bacterial cell surface appendages, known as pili, have been recently described in streptococcal pathogens, including GBS. The pilus tip adhesin, PilA, contributes to GBS adherence to blood-brain barrier (BBB) endothel...

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Detalles Bibliográficos
Autores principales: Banerjee, Anirban, Kim, Brandon J., Carmona, Ellese M., Cutting, Andrew S., Gurney, Michael A., Carlos, Chris, Feuer, Ralph, Prasadarao, Nemani V., Doran, Kelly S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3195231/
https://www.ncbi.nlm.nih.gov/pubmed/21897373
http://dx.doi.org/10.1038/ncomms1474