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Bacterial Pili exploit integrin machinery to promote immune activation and efficient blood-brain barrier penetration
Group B Streptococcus (GBS) is the leading cause of meningitis in newborn infants. Bacterial cell surface appendages, known as pili, have been recently described in streptococcal pathogens, including GBS. The pilus tip adhesin, PilA, contributes to GBS adherence to blood-brain barrier (BBB) endothel...
Autores principales: | Banerjee, Anirban, Kim, Brandon J., Carmona, Ellese M., Cutting, Andrew S., Gurney, Michael A., Carlos, Chris, Feuer, Ralph, Prasadarao, Nemani V., Doran, Kelly S. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2011
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3195231/ https://www.ncbi.nlm.nih.gov/pubmed/21897373 http://dx.doi.org/10.1038/ncomms1474 |
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