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Role of the NMDA-receptor in Prepulse Inhibition in the Rat

Kynurenic acid (KYNA) is an endogenous metabolite of tryptophan. Studies have revealed increased brain KYNA levels in patients with schizophrenia. Prepulse inhibition (PPI) is a behavioral model for sensorimotor gating and found to be reduced in schizophrenia. Previous studies have shown that pharma...

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Detalles Bibliográficos
Autores principales: Linderholm, Klas, Powell, Susan, Olsson, Elin, Holtze, Maria, Snodgrass, Ralph, Erhardt, Sophie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Libertas Academica 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3195246/
https://www.ncbi.nlm.nih.gov/pubmed/22084584