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A shift of the TOR adaptor from Rictor towards Raptor by semaphorin in C. elegans

The target of rapamycin (TOR), a central regulator for cell growth and metabolism, resides in the two functionally distinct complexes TORC1 and TORC2, which are defined by their adaptors Raptor and Rictor, respectively. How the formation of the two TORCs is orchestrated remains unclear. Here we show...

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Detalles Bibliográficos
Autores principales: Nukazuka, Akira, Tamaki, Shusaku, Matsumoto, Kunihiro, Oda, Yoichi, Fujisawa, Hajime, Takagi, Shin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3195255/
https://www.ncbi.nlm.nih.gov/pubmed/21952218
http://dx.doi.org/10.1038/ncomms1495