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A human Phase I/IIa malaria challenge trial of a polyprotein malaria vaccine

We examined the safety, immunogenicity and efficacy of a prime-boost vaccination regime involving two poxvirus malaria subunit vaccines, FP9-PP and MVA-PP, expressing the same polyprotein consisting of six pre-erythrocytic antigens from Plasmodium falciparum. Following safety assessment of single do...

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Detalles Bibliográficos
Autores principales: Porter, David W., Thompson, Fiona M., Berthoud, Tamara K., Hutchings, Claire L., Andrews, Laura, Biswas, Sumi, Poulton, Ian, Prieur, Eric, Correa, Simon, Rowland, Rosalind, Lang, Trudie, Williams, Jackie, Gilbert, Sarah C., Sinden, Robert E., Todryk, Stephen, Hill, Adrian V.S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier Science 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3195259/
https://www.ncbi.nlm.nih.gov/pubmed/21501642
http://dx.doi.org/10.1016/j.vaccine.2011.03.083