Vitamin K supplementation increases vitamin K tissue levels but fails to counteract ectopic calcification in a mouse model for pseudoxanthoma elasticum

Pseudoxanthoma elasticum (PXE) is an autosomal recessive disorder in which calcification of connective tissue leads to pathology in skin, eye and blood vessels. PXE is caused by mutations in ABCC6. High expression of this transporter in the basolateral hepatocyte membrane suggests that it secretes a...

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Detalles Bibliográficos
Autores principales: Gorgels, Theo G. M. F., Waarsing, Jan H., Herfs, Marjolein, Versteeg, Daniëlle, Schoensiegel, Frank, Sato, Toshiro, Schlingemann, Reinier O., Ivandic, Boris, Vermeer, Cees, Schurgers, Leon J., Bergen, Arthur A. B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer-Verlag 2011
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3195265/
https://www.ncbi.nlm.nih.gov/pubmed/21725681
http://dx.doi.org/10.1007/s00109-011-0782-y

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3195265/
https://www.ncbi.nlm.nih.gov/pubmed/21725681
http://dx.doi.org/10.1007/s00109-011-0782-y

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