Rationale for Targeting CD6 as a Treatment for Autoimmune Diseases

CD6 is a 105–130 kDa surface glycoprotein expressed on the majority of T cells and a subset of B cells. The human cd6 gene maps to chromosome 11, and the expression of its protein product is tightly regulated. CD6 mediates cellular adhesion migration across the endothelial and epithelial cells. In a...

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Detalles Bibliográficos
Autores principales: Alonso-Ramirez, Ruby, Loisel, Séverine, Buors, Caroline, Pers, Jacques-Olivier, Montero, Enrique, Youinou, Pierre, Renaudineau, Yves
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2010
Materias:
Review Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3195340/
https://www.ncbi.nlm.nih.gov/pubmed/22076177
http://dx.doi.org/10.1155/2010/130646

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3195340/
https://www.ncbi.nlm.nih.gov/pubmed/22076177
http://dx.doi.org/10.1155/2010/130646

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