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Function of the CysD domain of the gel-forming MUC2 mucin

The colonic human MUC2 mucin forms a polymeric gel by covalent disulfide bonds in its N- and C-termini. The middle part of MUC2 is largely composed of two highly O-glycosylated mucin domains that are interrupted by a CysD domain of unknown function. We studied its function as recombinant proteins fu...

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Detalles Bibliográficos
Autores principales: Ambort, Daniel, van der Post, Sjoerd, Johansson, Malin E. V., MacKenzie, Jenny, Thomsson, Elisabeth, Krengel, Ute, Hansson, Gunnar C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Portland Press Ltd. 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3195396/
https://www.ncbi.nlm.nih.gov/pubmed/21338337
http://dx.doi.org/10.1042/BJ20102066