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Autoradiographic Mapping of 5-H T (1B/1D) Binding Sites in the Rhesus Monkey Brain Using [carbonyl-(11)C]zolmitriptan

Zolmitriptan is a serotonin 5-HT(1B/1D) receptor agonist that is an effective and well-tolerated drug for migraine treatment. In a human positron emission tomography study, [(11)C]zolmitriptan crossed the blood-brain barrier but no clear pattern of regional uptake was discernable. The objective of t...

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Detalles Bibliográficos
Autores principales: Lindhe, Örjan, Almqvist, Per, Kågedal, Matts, Gustafsson, Sven-Åke, Bergström, Mats, Nilsson, Dag, Antoni, Gunnar
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3195497/
https://www.ncbi.nlm.nih.gov/pubmed/22013519
http://dx.doi.org/10.1155/2011/694179