Alzheimer-specific variants in the 3'UTR of Amyloid precursor protein affect microRNA function

BACKGROUND: APP expression misregulation can cause genetic Alzheimer's disease (AD). Recent evidences support the hypothesis that polymorphisms located in microRNA (miRNA) target sites could influence the risk of developing neurodegenerative disorders such as Parkinson's disease (PD) and f...

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Detalles Bibliográficos
Autores principales: Delay, Charlotte, Calon, Frédéric, Mathews, Paul, Hébert, Sébastien S
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2011
Materias:
Short Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3195754/
https://www.ncbi.nlm.nih.gov/pubmed/21982160
http://dx.doi.org/10.1186/1750-1326-6-70

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3195754/
https://www.ncbi.nlm.nih.gov/pubmed/21982160
http://dx.doi.org/10.1186/1750-1326-6-70

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