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Downregulation of the Adenosine A2b Receptor by RNA Interference Inhibits Hepatocellular Carcinoma Cell Growth

To investigate the biological effect of adenosine A2b receptor (A2bR) on the human hepatocellular carcinoma cell line HepG2, three A2bR siRNA constructs were transiently transfected into HepG2 cells. The results showed that A2bR siRNA reduced the levels of A2bR mRNA and protein. In order to further...

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Detalles Bibliográficos
Autores principales: Xiang, Hong-Jun, Chai, Fu-Lu, Wang, De-Sheng, Dou, Ke-Feng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: International Scholarly Research Network 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3195956/
https://www.ncbi.nlm.nih.gov/pubmed/22091434
http://dx.doi.org/10.5402/2011/875684