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Tryptophan in Alcoholism Treatment II:  Inhibition of the Rat Liver Mitochondrial Low K(m) Aldehyde Dehydrogenase Activity, Elevation of Blood Acetaldehyde Concentration and Induction of Aversion to Alcohol by Combined Administration of Tryptophan and Benserazide

Aims: The aims were to provide proofs of mechanism and principle by establishing the ability of the amino acid L-tryptophan (Trp) combined with the kynureninase inhibitor benserazide (BSZ) to inhibit the liver mitochondrial low K(m) aldehyde dehydrogenase (ALDH) activity after administration and in...

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Detalles Bibliográficos
Autores principales: Badawy, Abdulla A.-B., Bano, Samina, Steptoe, Alex
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3196367/
https://www.ncbi.nlm.nih.gov/pubmed/21896551
http://dx.doi.org/10.1093/alcalc/agr135