Fitting the Elementary Rate Constants of the P-gp Transporter Network in the hMDR1-MDCK Confluent Cell Monolayer Using a Particle Swarm Algorithm

P-glycoprotein, a human multidrug resistance transporter, has been extensively studied due to its importance to human health and disease. In order to understand transport kinetics via P-gp, confluent cell monolayers overexpressing P-gp are widely used. The purpose of this study is to obtain the mass...

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Detalles Bibliográficos
Autores principales: Agnani, Deep, Acharya, Poulomi, Martinez, Esteban, Tran, Thuy Thanh, Abraham, Feby, Tobin, Frank, Ellens, Harma, Bentz, Joe
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3196501/
https://www.ncbi.nlm.nih.gov/pubmed/22028772
http://dx.doi.org/10.1371/journal.pone.0025086

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3196501/
https://www.ncbi.nlm.nih.gov/pubmed/22028772
http://dx.doi.org/10.1371/journal.pone.0025086

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