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The Adaptor Protein SH2B3 (Lnk) Negatively Regulates Neurite Outgrowth of PC12 Cells and Cortical Neurons

SH2B adaptor protein family members (SH2B1-3) regulate various physiological responses through affecting signaling, gene expression, and cell adhesion. SH2B1 and SH2B2 were reported to enhance nerve growth factor (NGF)-induced neuronal differentiation in PC12 cells, a well-established neuronal model...

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Detalles Bibliográficos
Autores principales: Wang, Tien-Cheng, Chiu, Hsun, Chang, Yu-Jung, Hsu, Tai-Yu, Chiu, Ing-Ming, Chen, Linyi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3196555/
https://www.ncbi.nlm.nih.gov/pubmed/22028877
http://dx.doi.org/10.1371/journal.pone.0026433