Assessing Antiangiogenic Therapy Response by DCE-MRI: Development of a Physiology Driven Multi-Compartment Model Using Population Pharmacometrics

Dynamic contrast enhanced (DCE-) MRI is commonly applied for the monitoring of antiangiogenic therapy in oncology. Established pharmacokinetic (PK) analysis methods of DCE-MRI data do not sufficiently reflect the complex anatomical and physiological constituents of the analyzed tissue. Hence, accept...

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Detalles Bibliográficos
Autores principales: Steingoetter, Andreas, Menne, Dieter, Braren, Rickmer F.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3196562/
https://www.ncbi.nlm.nih.gov/pubmed/22028864
http://dx.doi.org/10.1371/journal.pone.0026366

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3196562/
https://www.ncbi.nlm.nih.gov/pubmed/22028864
http://dx.doi.org/10.1371/journal.pone.0026366

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