Cargando…

Probing the Functional Mechanism of Escherichia coli GroEL Using Circular Permutation

BACKGROUND: The Escherichia coli chaperonin GroEL subunit consists of three domains linked via two hinge regions, and each domain is responsible for a specific role in the functional mechanism. Here, we have used circular permutation to study the structural and functional characteristics of the GroE...

Descripción completa

Detalles Bibliográficos
Autores principales: Mizobata, Tomohiro, Uemura, Tatsuya, Isaji, Kazuhiro, Hirayama, Takuma, Hongo, Kunihiro, Kawata, Yasushi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3196576/
https://www.ncbi.nlm.nih.gov/pubmed/22028884
http://dx.doi.org/10.1371/journal.pone.0026462