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Probing the Functional Mechanism of Escherichia coli GroEL Using Circular Permutation
BACKGROUND: The Escherichia coli chaperonin GroEL subunit consists of three domains linked via two hinge regions, and each domain is responsible for a specific role in the functional mechanism. Here, we have used circular permutation to study the structural and functional characteristics of the GroE...
Autores principales: | Mizobata, Tomohiro, Uemura, Tatsuya, Isaji, Kazuhiro, Hirayama, Takuma, Hongo, Kunihiro, Kawata, Yasushi |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2011
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3196576/ https://www.ncbi.nlm.nih.gov/pubmed/22028884 http://dx.doi.org/10.1371/journal.pone.0026462 |
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