Inosine-Containing RNA Is a Novel Innate Immune Recognition Element and Reduces RSV Infection

During viral infections, single- and double-stranded RNA (ssRNA and dsRNA) are recognized by the host and induce innate immune responses. The cellular enzyme ADAR-1 (adenosine deaminase acting on RNA-1) activation in virally infected cells leads to presence of inosine-containing RNA (Ino-RNA). Here...

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Detalles Bibliográficos
Autores principales: Liao, Jie-ying, Thakur, Sheetal A., Zalinger, Zachary B., Gerrish, Kevin E., Imani, Farhad
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3196583/
https://www.ncbi.nlm.nih.gov/pubmed/22028885
http://dx.doi.org/10.1371/journal.pone.0026463

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3196583/
https://www.ncbi.nlm.nih.gov/pubmed/22028885
http://dx.doi.org/10.1371/journal.pone.0026463

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