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Inosine-Containing RNA Is a Novel Innate Immune Recognition Element and Reduces RSV Infection
During viral infections, single- and double-stranded RNA (ssRNA and dsRNA) are recognized by the host and induce innate immune responses. The cellular enzyme ADAR-1 (adenosine deaminase acting on RNA-1) activation in virally infected cells leads to presence of inosine-containing RNA (Ino-RNA). Here...
| Autores principales: | , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Public Library of Science
2011
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3196583/ https://www.ncbi.nlm.nih.gov/pubmed/22028885 http://dx.doi.org/10.1371/journal.pone.0026463 |