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Evaluation of the Ability of LL-37 to Neutralise LPS In Vitro and Ex Vivo

BACKGROUND: Human cathelicidin LL-37 is a cationic antimicrobial peptide (AMP) which possesses a variety of activities including the ability to neutralise endotoxin. In this study, we investigated the role of LPS neutralisation in mediating LL-37's ability to inhibit Pseudomonas aeruginosa LPS...

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Detalles Bibliográficos
Autores principales: Scott, Aaron, Weldon, Sinéad, Buchanan, Paul J., Schock, Bettina, Ernst, Robert K., McAuley, Danny F., Tunney, Michael M., Irwin, Chris R., Elborn, J. Stuart, Taggart, Clifford C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3196584/
https://www.ncbi.nlm.nih.gov/pubmed/22028895
http://dx.doi.org/10.1371/journal.pone.0026525