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Evaluation of the Ability of LL-37 to Neutralise LPS In Vitro and Ex Vivo
BACKGROUND: Human cathelicidin LL-37 is a cationic antimicrobial peptide (AMP) which possesses a variety of activities including the ability to neutralise endotoxin. In this study, we investigated the role of LPS neutralisation in mediating LL-37's ability to inhibit Pseudomonas aeruginosa LPS...
Autores principales: | Scott, Aaron, Weldon, Sinéad, Buchanan, Paul J., Schock, Bettina, Ernst, Robert K., McAuley, Danny F., Tunney, Michael M., Irwin, Chris R., Elborn, J. Stuart, Taggart, Clifford C. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2011
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3196584/ https://www.ncbi.nlm.nih.gov/pubmed/22028895 http://dx.doi.org/10.1371/journal.pone.0026525 |
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