Clopidogrel, a P2Y12 Receptor Antagonist, Potentiates the Inflammatory Response in a Rat Model of Peptidoglycan Polysaccharide-Induced Arthritis

The P2Y12 receptor plays a crucial role in the regulation of platelet activation by several agonists, which is irreversibly antagonized by the active metabolite of clopidogrel, a widely used anti-thrombotic drug. In this study, we investigated whether reduction of platelet reactivity leads to reduce...

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Detalles Bibliográficos
Autores principales: Garcia, Analia E., Mada, Sripal R., Rico, Mario C., Dela Cadena, Raul A., Kunapuli, Satya P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3196585/
https://www.ncbi.nlm.nih.gov/pubmed/22028806
http://dx.doi.org/10.1371/journal.pone.0026035

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3196585/
https://www.ncbi.nlm.nih.gov/pubmed/22028806
http://dx.doi.org/10.1371/journal.pone.0026035

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