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Fluorescent Peptide Biosensor for Probing the Relative Abundance of Cyclin-Dependent Kinases in Living Cells

Cyclin-dependant kinases play a central role in coordinating cell growth and division, and in sustaining proliferation of cancer cells, thereby constituting attractive pharmacological targets. However, there are no direct means of assessing their relative abundance in living cells, current approache...

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Detalles Bibliográficos
Autores principales: Kurzawa, Laetitia, Pellerano, Morgan, Coppolani, J. B., Morris, May C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3196589/
https://www.ncbi.nlm.nih.gov/pubmed/22028905
http://dx.doi.org/10.1371/journal.pone.0026555