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Towards the development of novel Trypanosoma brucei RNA editing ligase 1 inhibitors
BACKGROUND: Trypanosoma brucei (T. brucei) is an infectious agent for which drug development has been largely neglected. We here use a recently developed computer program called AutoGrow to add interacting molecular fragments to S5, a known inhibitor of the validated T. brucei drug target RNA editin...
Autores principales: | , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2011
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3196686/ https://www.ncbi.nlm.nih.gov/pubmed/21878090 http://dx.doi.org/10.1186/1471-2210-11-9 |