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Comparative analysis of the human hepatic and adipose tissue transcriptomes during LPS-induced inflammation leads to the identification of differential biological pathways and candidate biomarkers

BACKGROUND: Insulin resistance (IR) is accompanied by chronic low grade systemic inflammation, obesity, and deregulation of total body energy homeostasis. We induced inflammation in adipose and liver tissues in vitro in order to mimic inflammation in vivo with the aim to identify tissue-specific pro...

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Detalles Bibliográficos
Autores principales: Szalowska, Ewa, Dijkstra, Martijn, Elferink, Marieke GL, Weening, Desiree, de Vries, Marcel, Bruinenberg, Marcel, Hoek, Annemieke, Roelofsen, Han, Groothuis, Geny MM, Vonk, Roel J
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3196688/
https://www.ncbi.nlm.nih.gov/pubmed/21978410
http://dx.doi.org/10.1186/1755-8794-4-71