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Unveiling novel genes upregulated by both rhBMP2 and rhBMP7 during early osteoblastic transdifferentiation of C2C12 cells

FINDINGS: We set out to analyse the gene expression profile of pre-osteoblastic C2C12 cells during osteodifferentiation induced by both rhBMP2 and rhBMP7 using DNA microarrays. Induced and repressed genes were intercepted, resulting in 1,318 induced genes and 704 repressed genes by both rhBMP2 and r...

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Detalles Bibliográficos
Autores principales: Bustos-Valenzuela, Juan C, Fujita, Andre, Halcsik, Erik, Granjeiro, Jose M, Sogayar, Mari C
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3196718/
https://www.ncbi.nlm.nih.gov/pubmed/21943021
http://dx.doi.org/10.1186/1756-0500-4-370