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Increased levels of noisy splicing in cancers, but not for oncogene-derived transcripts
Recent genome-wide analyses have detected numerous cancer-specific alternative splicing (AS) events. Whether transcripts containing cancer-specific AS events are likely to be translated into functional proteins or simply reflect noisy splicing, thereby determining their clinical relevance, is not kn...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2011
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3196890/ https://www.ncbi.nlm.nih.gov/pubmed/21862452 http://dx.doi.org/10.1093/hmg/ddr370 |