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Increased levels of noisy splicing in cancers, but not for oncogene-derived transcripts

Recent genome-wide analyses have detected numerous cancer-specific alternative splicing (AS) events. Whether transcripts containing cancer-specific AS events are likely to be translated into functional proteins or simply reflect noisy splicing, thereby determining their clinical relevance, is not kn...

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Detalles Bibliográficos
Autores principales: Chen, Lu, Tovar-Corona, Jaime M., Urrutia, Araxi O.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3196890/
https://www.ncbi.nlm.nih.gov/pubmed/21862452
http://dx.doi.org/10.1093/hmg/ddr370