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Brain region specific mitophagy capacity could contribute to selective neuronal vulnerability in Parkinson's disease
Parkinson's disease (PD) is histologically well defined by its characteristic degeneration of dopaminergic neurons in the substantia nigra pars compacta. Remarkably, divergent PD-related mutations can generate comparable brain region specific pathologies. This indicates that some intrinsic regi...
Autores principales: | Diedrich, Madeleine, Kitada, Tohru, Nebrich, Grit, Koppelstaetter, Andrea, Shen, Jie, Zabel, Claus, Klose, Joachim, Mao, Lei |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2011
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3196908/ https://www.ncbi.nlm.nih.gov/pubmed/21943346 http://dx.doi.org/10.1186/1477-5956-9-59 |
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