Targeting HSP90 in ovarian cancers with multiple receptor tyrosine kinase coactivation

BACKGROUND: Ovarian cancer has the highest mortality rate of all gynecologic malignancy. The receptor tyrosine kinases (RTKs), including EGFR, ERBB2, PDGFR, VEGFR and MET, are activated in subsets of ovarian cancer, suggesting that these kinases might represent novel therapeutic targets. However, cl...

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Detalles Bibliográficos
Autores principales: Jiao, Yisheng, Ou, Wenbin, Meng, Fanguo, Zhou, Haimeng, Wang, Aiyuan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2011
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3196924/
https://www.ncbi.nlm.nih.gov/pubmed/21962244
http://dx.doi.org/10.1186/1476-4598-10-125

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3196924/
https://www.ncbi.nlm.nih.gov/pubmed/21962244
http://dx.doi.org/10.1186/1476-4598-10-125

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