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A Strategy to Identify de Novo Mutations in Common Disorders such as Autism and Schizophrenia
There are several lines of evidence supporting the role of de novo mutations as a mechanism for common disorders, such as autism and schizophrenia. First, the de novo mutation rate in humans is relatively high, so new mutations are generated at a high frequency in the population. However, de novo mu...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MyJove Corporation
2011
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3197027/ https://www.ncbi.nlm.nih.gov/pubmed/21712793 http://dx.doi.org/10.3791/2534 |