Chronic Morphine Alters the Presynaptic Protein Profile: Identification of Novel Molecular Targets Using Proteomics and Network Analysis

Opiates produce significant and persistent changes in synaptic transmission; knowledge of the proteins involved in these changes may help to understand the molecular mechanisms underlying opiate dependence. Using an integrated quantitative proteomics and systems biology approach, we explored changes...

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Detalles Bibliográficos
Autores principales: Abul-Husn, Noura S., Annangudi, Suresh P., Ma'ayan, Avi, Ramos-Ortolaza, Dinah L., Stockton, Steven D., Gomes, Ivone, Sweedler, Jonathan V., Devi, Lakshmi A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3197197/
https://www.ncbi.nlm.nih.gov/pubmed/22043286
http://dx.doi.org/10.1371/journal.pone.0025535

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3197197/
https://www.ncbi.nlm.nih.gov/pubmed/22043286
http://dx.doi.org/10.1371/journal.pone.0025535

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