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A paired-end sequencing strategy to map the complex landscape of transcription initiation

Recent high-throughput sequencing protocols have uncovered the complexity of mammalian transcription by RNA polymerase II, helping to define several initiation patterns in which transcription start sites (TSSs) cluster within both narrow and broad genomic windows. Here, we describe a paired-end sequ...

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Detalles Bibliográficos
Autores principales: Ni, Ting, Corcoran, David L, Rach, Elizabeth A, Song, Shen, Spana, Eric P, Gao, Yuan, Ohler, Uwe, Zhu, Jun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3197272/
https://www.ncbi.nlm.nih.gov/pubmed/20495556
http://dx.doi.org/10.1038/nmeth.1464