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A paired-end sequencing strategy to map the complex landscape of transcription initiation
Recent high-throughput sequencing protocols have uncovered the complexity of mammalian transcription by RNA polymerase II, helping to define several initiation patterns in which transcription start sites (TSSs) cluster within both narrow and broad genomic windows. Here, we describe a paired-end sequ...
Autores principales: | , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
2010
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3197272/ https://www.ncbi.nlm.nih.gov/pubmed/20495556 http://dx.doi.org/10.1038/nmeth.1464 |