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Orthotopic Xenografting of Human Luciferase-Tagged Malignant Peripheral Nerve Sheath Tumor Cells for in vivo Testing of Candidate Therapeutic Agents

Although in vitro screens are essential for the initial identification of candidate therapeutic agents, a rigorous assessment of the drug's ability to inhibit tumor growth must be performed in a suitable animal model. The type of animal model that is best for this purpose is a topic of intense...

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Detalles Bibliográficos
Autores principales: Turk, Amy N., Byer, Stephanie J., Zinn, Kurt R., Carroll, Steven L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MyJove Corporation 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3197311/
https://www.ncbi.nlm.nih.gov/pubmed/21460792
http://dx.doi.org/10.3791/2558