Activation of Pak1/Akt/eNOS signaling following sphingosine-1-phosphate release as part of a mechanism protecting cardiomyocytes against ischemic cell injury

We investigated whether plasma long-chain sphingoid base (LCSB) concentrations are altered by transient cardiac ischemia during percutaneous coronary intervention (PCI) in humans and examined the signaling through the sphingosine-1-phosphate (S1P) cascade as a mechanism underlying the S1P cardioprot...

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Detalles Bibliográficos
Autores principales: Egom, Emmanuel Eroume A., Mohamed, Tamer M. A., Mamas, Mamas A., Shi, Ying, Liu, Wei, Chirico, Debora, Stringer, Sally E., Ke, Yunbo, Shaheen, Mohamed, Wang, Tao, Chacko, Sanoj, Wang, Xin, Solaro, R. John, Fath-Ordoubadi, Farzin, Cartwright, Elizabeth J., Lei, Ming
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Physiological Society 2011
Materias:
Signaling and Stress Response
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3197364/
https://www.ncbi.nlm.nih.gov/pubmed/21705677
http://dx.doi.org/10.1152/ajpheart.01003.2010

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3197364/
https://www.ncbi.nlm.nih.gov/pubmed/21705677
http://dx.doi.org/10.1152/ajpheart.01003.2010

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