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β-Lapachone induces heart morphogenetic and functional defects by promoting the death of erythrocytes and the endocardium in zebrafish embryos

BACKGROUND: β-Lapachone has antitumor and wound healing-promoting activities. To address the potential influences of various chemicals on heart development of zebrafish embryos, we previously treated zebrafish embryos with chemicals from a Sigma LOPAC1280™ library and found several chemicals includi...

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Detalles Bibliográficos
Autores principales: Wu, Yi-Ting, Lin, Che Yi, Tsai, Ming-Yuan, Chen, Yi-Hua, Lu, Yu-Fen, Huang, Chang-Jen, Cheng, Chao-Min, Hwang, Sheng-Ping L
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3197495/
https://www.ncbi.nlm.nih.gov/pubmed/21936955
http://dx.doi.org/10.1186/1423-0127-18-70