Changes in Capsular Serotype Alter the Surface Exposure of Pneumococcal Adhesins and Impact Virulence

We examined the contribution of serotype on Streptococcus pneumoniae adhesion and virulence during respiratory tract infection using a panel of isogenic TIGR4 (serotype 4) mutants expressing the capsule types 6A (+6A), 7F (+7F) and 23F (+23F) as well as a deleted and restored serotype 4 (+4) control...

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Detalles Bibliográficos
Autores principales: Sanchez, Carlos J., Hinojosa, Cecilia A., Shivshankar, Pooja, Hyams, Catherine, Camberlein, Emilie, Brown, Jeremy S., Orihuela, Carlos J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3197518/
https://www.ncbi.nlm.nih.gov/pubmed/22028914
http://dx.doi.org/10.1371/journal.pone.0026587

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3197518/
https://www.ncbi.nlm.nih.gov/pubmed/22028914
http://dx.doi.org/10.1371/journal.pone.0026587

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