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Changes in Capsular Serotype Alter the Surface Exposure of Pneumococcal Adhesins and Impact Virulence
We examined the contribution of serotype on Streptococcus pneumoniae adhesion and virulence during respiratory tract infection using a panel of isogenic TIGR4 (serotype 4) mutants expressing the capsule types 6A (+6A), 7F (+7F) and 23F (+23F) as well as a deleted and restored serotype 4 (+4) control...
Autores principales: | Sanchez, Carlos J., Hinojosa, Cecilia A., Shivshankar, Pooja, Hyams, Catherine, Camberlein, Emilie, Brown, Jeremy S., Orihuela, Carlos J. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2011
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3197518/ https://www.ncbi.nlm.nih.gov/pubmed/22028914 http://dx.doi.org/10.1371/journal.pone.0026587 |
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