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Endogenous Epoxygenases Are Modulators of Monocyte/Macrophage Activity

BACKGROUND: Arachidonic acid is metabolized through three major metabolic pathways, the cyclooxygenase, lipoxygenase and CYP450 enzyme systems. Unlike cyclooxygenase and lipoxygenases, the role of CYP450 epoxygenases in monocyte/macrophage-mediated responses is not known. METHODOLOGY/PRINCIPAL FINDI...

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Detalles Bibliográficos
Autores principales: Bystrom, Jonas, Wray, Jessica A., Sugden, Mary C., Holness, Mark J., Swales, Karen E., Warner, Timothy D., Edin, Matthew L., Zeldin, Darryl C., Gilroy, Derek W., Bishop-Bailey, David
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3197524/
https://www.ncbi.nlm.nih.gov/pubmed/22028915
http://dx.doi.org/10.1371/journal.pone.0026591