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Endogenous Epoxygenases Are Modulators of Monocyte/Macrophage Activity
BACKGROUND: Arachidonic acid is metabolized through three major metabolic pathways, the cyclooxygenase, lipoxygenase and CYP450 enzyme systems. Unlike cyclooxygenase and lipoxygenases, the role of CYP450 epoxygenases in monocyte/macrophage-mediated responses is not known. METHODOLOGY/PRINCIPAL FINDI...
Autores principales: | Bystrom, Jonas, Wray, Jessica A., Sugden, Mary C., Holness, Mark J., Swales, Karen E., Warner, Timothy D., Edin, Matthew L., Zeldin, Darryl C., Gilroy, Derek W., Bishop-Bailey, David |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2011
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3197524/ https://www.ncbi.nlm.nih.gov/pubmed/22028915 http://dx.doi.org/10.1371/journal.pone.0026591 |
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