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A mathematical model for targeting chemicals to tissues by exploiting complex degradation

BACKGROUND: In many biological and therapeutic contexts, it is highly desirable to target a chemical specifically to a particular tissue where it exerts its biological effect. In this paper, we present a simple, generic, mathematical model that elucidates a general method for targeting a chemical to...

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Detalles Bibliográficos
Autores principales: Gardiner, Bruce S, Zhang, Lihai, Smith, David W, Pivonka, Peter, Grodzinsky, Alan J
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3197567/
https://www.ncbi.nlm.nih.gov/pubmed/21936951
http://dx.doi.org/10.1186/1745-6150-6-46