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Instability of the Octarepeat Region of the Human Prion Protein Gene

Prion diseases are a family of unique fatal transmissible neurodegenerative diseases that affect humans and many animals. Sporadic Creutzfeldt-Jakob disease (sCJD) is the most common prion disease in humans, accounting for 85–90% of all human prion cases, and exhibits a high degree of diversity in p...

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Detalles Bibliográficos
Autores principales: Li, Baiya, Qing, Liuting, Yan, Jianqun, Kong, Qingzhong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3197570/
https://www.ncbi.nlm.nih.gov/pubmed/22028931
http://dx.doi.org/10.1371/journal.pone.0026635