Effects of DAPT and Atoh1 Overexpression on Hair Cell Production and Hair Bundle Orientation in Cultured Organ of Corti from Neonatal Rats

BACKGROUND: In mammals, hair cells do not undergo spontaneous regeneration when they are damaged and result in permanent hearing loss. Previous studies in cultured Organ of Corti dissected from neonatal animals have shown that both DAPT (r-secretase inhibitor in the Notch signal pathway) treatment a...

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Detalles Bibliográficos
Autores principales: Zhao, Li-Dong, Guo, Wei-Wei, Lin, Chang, Li, Li-Xian, Sun, Jian-He, Wu, Nan, Ren, Li-Li, Li, Xin-Xin, Liu, Hui-Zhan, Young, Wie-Yen, Gao, Wei-Qiang, Yang, Shi-Ming
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3197578/
https://www.ncbi.nlm.nih.gov/pubmed/22028767
http://dx.doi.org/10.1371/journal.pone.0023729

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3197578/
https://www.ncbi.nlm.nih.gov/pubmed/22028767
http://dx.doi.org/10.1371/journal.pone.0023729

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