Cross-Platform Array Screening Identifies COL1A2, THBS1, TNFRSF10D and UCHL1 as Genes Frequently Silenced by Methylation in Melanoma

Epigenetic regulation of tumor suppressor genes (TSGs) has been shown to play a central role in melanomagenesis. By integrating gene expression and methylation array analysis we identified novel candidate genes frequently methylated in melanoma. We validated the methylation status of the most promis...

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Detalles Bibliográficos
Autores principales: Bonazzi, Vanessa F., Nancarrow, Derek J., Stark, Mitchell S., Moser, Ralf J., Boyle, Glen M., Aoude, Lauren G., Schmidt, Christopher, Hayward, Nicholas K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3197591/
https://www.ncbi.nlm.nih.gov/pubmed/22028813
http://dx.doi.org/10.1371/journal.pone.0026121

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3197591/
https://www.ncbi.nlm.nih.gov/pubmed/22028813
http://dx.doi.org/10.1371/journal.pone.0026121

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