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Cross-Platform Array Screening Identifies COL1A2, THBS1, TNFRSF10D and UCHL1 as Genes Frequently Silenced by Methylation in Melanoma
Epigenetic regulation of tumor suppressor genes (TSGs) has been shown to play a central role in melanomagenesis. By integrating gene expression and methylation array analysis we identified novel candidate genes frequently methylated in melanoma. We validated the methylation status of the most promis...
Autores principales: | Bonazzi, Vanessa F., Nancarrow, Derek J., Stark, Mitchell S., Moser, Ralf J., Boyle, Glen M., Aoude, Lauren G., Schmidt, Christopher, Hayward, Nicholas K. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2011
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3197591/ https://www.ncbi.nlm.nih.gov/pubmed/22028813 http://dx.doi.org/10.1371/journal.pone.0026121 |
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